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Regional Innovation Fund (RIF)


The Regional Innovation Fund provided support to promote the adoption of innovation and the spread of best practice across the NHS. NHS England took over the management of the RIF in 2013 and ran two consecutive calls for 2013/14 and 2014/15 years funding 87 projects in total. The last funding call for projects closed in May 2014.

The fund provided an opportunity for the NHS to change lives, helping clinicians to work in new ways, and driving the changes that patients want to see. The RIF also encouraged strong partnerships with industry and third sector to drive the adoption of new technologies.

Click on the list below or use the browse option to view a selection of case studies produced by RIF teams.


Low Level Laser Therapy (LLLT)

Case study arrowLLLT is a local application of a special light source to treat radiotherapy induced inflammation of the lining of mouth (oral mucositis) in cancer patients undergoing radiotherapy treatment.

LLLT device in useOver 80% of chemoradiotherapy-treated patients experience this side effect causing severe pain and often requiring nutritional support. It is recommended as a treatment option in the Multinational Association for Supportive Care in cancer (MASCC) guidelines.

This project aimed to prevent development of oral mucositis, in our head and neck cancer patients significantly reducing pain, severity and duration of symptoms.

University Hospital Southampton NHS Foundation Trust has worked with THOR Photomedicine LTD to introduce this treatment into the clinical pathway

Data from the first 10 patients treated with LLLT, indicates that the analgesic requirements are significantly lower than patients treated with conservative methods. The patients treated with LLLT have has less incidence of inpatient hospital admissions (<20% when compared to standard patients around 40%)

None of the 10 patients treated by LLLT had interruptions to their radiotherapy treatment and managed to complete their radiotherapy within their prescribed time period. These patients also seem to require shorter duration of nasogastric tube feeding when compared to standard treatment (average of 4-6 weeks).

Award Value: £50,000

Funding source Logo


Contact Name Ramkumar Shanmugasundaram Email address robchesters1@gmail.com

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